About Us
The Science

The Science

NuCalm® is a proprietary clinical system that calms the brain within minutes by bringing alert beta brain wave function down to the alpha/theta ranges (deep relaxation). The system is predicated on neuropsychobiology and neurobioinformatics and was developed over eight years by leading neuroscientists.

NuCalm is unique because it creates deep relaxation without using narcotics or controlled substances, causes no significant side effects, and requires no recuperative time or supervision.

NuCalm organically entrains brain waves to a frequency that promotes relaxation and calm. Beta brain waves (13 Hz-30 Hz per second) are associated with day-to-day wakefulness - mental activity consisting of cognitive, sensory, and motor activities. High beta brain waves (23 Hz-40 Hz per second) are associated with fear and anxiety. NuCalm brings the patient's brain waves from beta or high beta to the alpha and theta ranges (4 Hz-12 Hz per second). Alpha brain waves are considered the first stage of sleep and are typically associated with relaxation and peacefulness during deep meditation and biofeedback. Alpha brain waves are characterized by slower frequencies, higher amplitudes, and are more synchronous than beta brain waves. A person with brain waves in the alpha range is physically unable to be anxious. NuCalm entrains the brain to the alpha/theta ranges, naturally creating homeostasis, neuromuscular release, and relaxation.

The patented NuCalm system leverages the synergistic benefits of four sensory applications:

  • Proprietary dietary supplements containing neurotransmitters that counteract adrenaline
  • CES (FDA-cleared Cranial Electrotherapy Stimulation) - research shows this helps facilitate a relaxation response
  • Proprietary neuroacoustic software to initiate changes in brain wave frequencies
  • Light-blocking eye mask to alert the central nervous system that you feel safe in your environment and it's safe to relax

NuCalm System

Dietary Supplements1
NuCalm topical cream

The NuCalm proprietary orthomolecular formula has been developed over several years to maximize the body’s natural relaxation response with NuCalm. The proprietary formula is only available in the NuCalm system and includes structured, nutrient-sourced building blocks that rapidly convert to powerful messengers that interrupt the stress response.

The supplementation comes in two forms: topical cream or dietary supplements.



Cranial Electrotherapy Stimulation (CES)
NuCalm CES Unit

The Cranial Electrotherapy Stimulation device produces low amounts of electrical current (close to the cell’s own electrical values - microcurrent is less than 1/10,000th of an Amp). This easy-to-use device has been cleared by the FDA for the treatment of anxiety, depression, and insomnia. Research over the past 50 years indicates an increase in metabolism of neurotransmitters as evidenced by an increase in the metabolites of the neurochemicals. Other research points to a normalization and balance of the brain’s neurochemistry by reestablishing optimal neurotransmitter levels. Low-level electrical current interacts with cell membranes in a manner that produces modifications in information transduction associated with classical second messenger pathways. Electrical engineering studies found that a small fraction of CES current actually reaches the thalamic area of the brain facilitating the release of neurotransmitters.

Combining CES with precursor neurotransmitters causes a profound state of relaxation and anxiolysis. QEEG and EEG’s indicate a brain wave shift occurring whereby the patient’s brain activity slows down - from beta brain waves of high alertness and anxiety to alpha brain waves that are present during a relaxed, pre-sleep state.

NuCalm Neuroacoustic SoftwareNuCalm Neuroacoustic Software

The proprietary neuroacoustic software provided in the NuCalm system uses Frequency-Following-Response (FFR) that initiates a change in brain waves. According to extensive research, a scientifically validated neurophysiologic response is initiated when an auditory pacing signal is presented to the brain. Solace Lifesciences has developed significant advances in the design of binaural and monaural beat sound acoustics, which are overlaid with classical music and presented through a stereo headset. The neuroacoustic brain entrainment software moves the patient’s brain waves from the high beta brain wave frequencies associated with anxiety (23 Hz-40 Hz) to brain wave frequency patterns of alpha and theta (4 Hz-12 Hz). These brain waves are associated with deep relaxation and calmness.

Binaural beats are auditory brainstem responses, which originate in the superior olivary nucleus of each hemisphere. They result from the interaction of two different auditory impulses, originating in opposite ears, registering below 1,000 Hz and which differ in frequency between one and 30 Hz (Oster, 1973). For example, if a pure tone of 500 Hz is presented to the right ear and a pure tone of 510 Hz is presented simultaneously to the left ear, an amplitude modulated standing wave of 10 Hz, the difference between the two tones, is experienced as the two wave forms mesh in and out of phase within the superior olivary nuclei. This binaural beat is not heard in the ordinary sense of the word (the human range of hearing is from 20-20,000 Hz). It is perceived as an auditory beat, and theoretically can be used to entrain specific neural rhythms through the frequency-following-response, thus modulating the brain wave frequency in the case of NuCalm between 4 Hz and 12 Hz.


NuCalm Light-Blocking Eye MaskNuCalm eye mask

NuCalm's light-blocking eye masks are used to block light from the optic nerve resulting in up to a 30% increase in alpha wave production in the occipital cortex of the brain. This helps maintain deep relaxation.





1 -  These statements have not been evaluated by the Food and Drug Administration. NuCalm is not intended to diagnose, treat, cure or prevent any disease.

NuCalm Performance Technology Overview

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“The NuCalm technology is exciting, with its awesome current applications, and the promise of beneficial future investigations.  The ability of NuCalm to reduce sympathetic discharge and its impact on the autonomic nervous system is clearly a freestanding and noteworthy contribution to society and our high-paced, stress-filled lives.  We know that every organ system in the human body is disturbed when sympathetic tone predominates excessively and chronically.  I can imagine a myriad of uses for NuCalm to demonstrate the immune-boosting role of shifting to a parasympathetic-dominated tone.”

Dr. Tarman Aziz