• Rapid induction of parasympathetic hypnagogic dissociative state
• Sustained, steady parasympathetic dominance throughout the NuCalm journey
• Rapid return to a functional state (motor skills, attention, and full cognition) with no lingering effects or mental lethargy

The biochemical signaling of the NuCalm clinical system includes a proprietary blend of inhibitory neurotransmitters, primarily GABA (Gamma-Aminobutyric Acid). GABA is the main inhibitory neurotransmitter in the central nervous system. GABAergic inhibition is seen at all levels of the CNS, including the hypothalamus, hippocampus, cerebral cortex, and cerebellar cortex. In addition to the large well established GABA pathways, GABA interneurons are abundant in the brain, with 50% of the inhibitory synapses in the brain being GABA mediated. In individuals with anxiety spectrum disorders or autonomic nervous system dysfunction these pathways are not optimally biologically functional. Anxiolytics will bind to the GABA receptors but do nothing to return the pathways to optimal function.

The NuCalm biosignal processing discs deliver the frequencies of GABA directly to the brain using resonance and biomodulation, like a tuning fork. This delivery mechanism overrides the body’s metabolic and absorption processes, including the challenge of penetrating the blood brain barrier. Every chemical has a signature frequency. Dr. Holloway worked with scientists in Germany and China for more than 4 years to identify the exact frequencies of the seven inhibitory neurotransmitters that were in the NuCalm transdermal cream. Once the specific frequencies were determined, it took over a year of trial and error and alchemy to adjust the frequency imprints to mimic the exact molecular formulation of the NuCalm transdermal cream. The NuCalm biosignal processing discs are then created by imprinting a signature frequency recipe inside a Tesla coil onto a six-layer Lakhovksy Multiwave Oscillator. The discs are protected from EMFs by being packaged in a Faraday bag.

Traditional Chinese Medicine explains that Qi (light energy) flows through the body along particular pathways, or Meridians, to maintain health. Everything in the world as we know it vibrates with a particular pattern, thus living systems produce electromagnetic frequencies endogenously that differ depending on the level of health or disease. It is hypothesized that if you can restore the frequencies that travel through the Meridians you can reinstate optimal physiology. Each NuCalm disc holds the electromagnetic frequency patterns of GABA and its precursors to deliver a pure biological signal to your body. When placed on the inside of your left wrist, at your Pericardium-6 acupuncture point, the disc sends a signal to the pericardium of your heart to activate local parasympathetic nerve fibers, which then transmit the signal to your brain telling it to increase vagal nerve output and begin the process of slowing down the body. The disc stops your acute stress response, so the brainwave entrainment with NuCalm’s patented neuroacoustic software is always reliable, fast acting, and efficient at getting you into Theta brain wave range, where cellular restoration and relaxation can take place.

Balancing the Brain’s Neurochemistry

A properly functioning GABAergic system is vital for relaxation, cellular restoration, and balance. NuCalm Rescue, PowerNap, and FlowState help reduce stress, promote recovery and generate calm by working at the root causes of the problem – the imbalanced neurochemical and neuroelectrical systems of the autonomic nervous system.

The brain’s chemical messengers or neurotransmitters are either excitatory, inhibitory or modulatory. The main excitatory neurotransmitter is glutamate, and its role is to potentiate signals forward and increase neuronal activity. The major inhibitory neurotransmitter, GABA, inhibits nerve activity by preventing signals from moving forward, thus calming the brain. It does this by interrupting the HPA and downregulating the secretion of adrenaline. The common neuromodulatory neurotransmitters are either serotonin or dopamine. Serotonin plays numerous important roles within the brain including regulating your mood, increasing your learning and memory, and is a chemical precursor for melatonin, an important sleep hormone. Dopamine is most well-known as the reward or pleasure chemical. Many studies have associated various neurological disorders with either the excess or deficit of a specific neurotransmitter. For example, increased dopamine levels have been found in people with addiction disorders, whereas decreased serotonin levels have been theorized to contribute to depression. Chronic stress is related to an improperly functioning GABAergic system that can no longer control the over-excitation and hyperactivity in the brain. Balance in neurochemical levels is the key to optimal brain health and function.