NuCalm was developed to resolve stress at the midbrain (the source of stress) for subjects suffering from acute Post-Traumatic Stress Disorder (PTSD) and addictive disease.

NuCalm is clinically proven to naturally relax the brain and body within minutes without drugs. This patented technology addresses the midbrain activities responsible for producing stress and anxiety by naturally mimicking the communication pathways used to prepare the body for sleep. NuCalm works on the GABAergic system to create a biomimetic negative feedback loop that reduces the action of the HPA axis (Hypothalamus – Anterior Pituitary Gland – Adrenal Gland). NuCalm is comprised of 4 discreet steps that work together to entrain brain wave function to the first stages of sleep and create parasympathetic nervous system dominance. People in the first stages of sleep are physically unable to have an anxious response. Within moments of application, people will not be experiencing the ‘fight-or-flight’ response, or releasing the stress hormone, cortisol.

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Anxiety is caused by a biological response to the stimulus of a threat, real or perceived. When a person is faced with a threat, the amygdala prepares the body by contacting an array of brain regions to activate the fight-or-flight system. The fight-or-flight response uses the sympathetic nervous system and the adrenal-cortical system to alert the body to speed up, tense up, become hypervigilant, and take action. The sympathetic nervous system triggers the release of epinephrine (adrenaline) and norepinephrine (noradrenaline) from the adrenal medulla into the bloodstream. These hormones increase heart rate and blood pressure. In parallel, the hypothalamus releases corticotropin-releasing factor (CRF) into the pituitary gland, which triggers the release of the adrenocorticotropic hormone (ACTH). ACTH travels through the blood stream to the adrenal cortex where it initiates the release of numerous hormones that prepare the body to respond to a threat. Once the fight-or-flight adrenaline response is activated, the mind cannot rationalize itself or self-regulate until the threat is removed and time passes.

The physiology of anxiety is characterized by cognitive, somatic, emotional, and behavioral components. These components combine to create feelings of fear, apprehension, and/or worry. Anxiety is often accompanied by physical sensations such as heart palpitations, nausea, chest pain, shortness of breath, stomach ache, cold and clammy feeling extremities, irritability, muscle tension, or headache. This is the dominant state of a person suffering from acute PTSD.

The neurophysiologic manifestations of NuCalm include the following:

  • Rapid induction of a parasympathetic hypnogogic dissociative state
  • Sustained, steady parasympathetic dominance throughout the experience
  • Rapid return to a functional state (motor skills, attention, and full cognition) with no lingering negative post-sedative effects


The autonomic nervous system (ANS) controls the bodily functions that occur without thinking – pupil dilations, salivation, heart rate, respiration, digestion, glucose release, gall bladder function, intestinal activity, urinary bladder function and sexual arousal.

The ANS is comprised of the parasympathetic nervous system and sympathetic nervous system. The sympathetic nervous system is activated when you are in a state of “fight or flight.” The parasympathetic nervous system is the “rest and digest” or “feed and breed” stage.

To achieve ANS balance (homeostasis), the parasympathetic and sympathetic nervous systems must be balanced. Due to the psychological stress that we have created for ourselves, most of us are sympathetically dominant. Why is this a problem? We all know that stress is bad for us – but what it actually means is that being sympathetically dominant for too long is bad for you. It means that you are not spending enough time in the parasympathetic state. High stress means that your adrenals are overactive. You are essentially poisoning your body with adrenaline. Appropriate adrenaline release will save your life; Overactive adrenals will slowly and silently kill you with exhaustion, poor sleep, poor recovery and a compromised immune system. If you are not spending enough time in the parasympathetic state, your body is depleting all of its resources without replenishing them. This is where NuCalm can help ensure that you are achieving ANS balance everyday. The more balanced you are, the stronger and healthier you will be.


What are brain wave lengths and how does NuCalm work with them?

The brain consists of millions of brain cells. These building blocks of the brain, called neurons, communicate with each through electrical charge.

When masses of neurons send synchronized electrical pulses, they produce a wave-like effect, or a brain wave.

Brain wave frequency is measured in Hertz (Hz), or cycles per second. High brain activity will produce high frequency brain waves.

As shown in the chart, Delta brain wave are the slowest (deep sleep). When we are awake, talking, in normal working consciousness, we are in beta brainwave length

As with all things in life, having a balance in brainwave activity is key to achieving optimal health and performance. We don’t want to spend too much or too little time in any frequency.

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NuCalm’s patented technology takes you to Theta brain wave length, which covers light sleep, REM sleep and the meditative state. NuCalm is basically meditation in a box. Now, everyone can meditate, with no effort. Theta is the optimal recovery zone. Spending adequate time in this phase everyday is essential to health. Again, without spending enough time in recovery zones, we are depleting our body’s resources daily, without replenishing them.

So, during NuCalm, you may dip into Delta if you are severely sleep deprived, but the majority of your session will be in Theta. Typically, people describe their NuCalm experience as being aware of what’s happening around them, but their body feels like it’s in deep sleep (slowed breathing, lower heart rate, heaviness of the body, with no movement).

Because NuCalm takes you so deep, so fast, so reliably, your body is able to receive many of the benefits of restorative sleep without actually being asleep.


The science behind NuCalm’s neuroacoustic software is remarkable and complex.

The objectives behind inventing the new NuCalm neuroacoustic software platform were to design physiologic outcomes focused on recovery, restoration, rebooting, and rebalancing… like fine-tuning a musical instrument.

Dr. Blake Holloway, inventor of NuCalm, spent several years immersed in the intriguing and exotic arena of quantum biology and neurophysics. New discoveries in neuroscience over the past decade have allowed him to develop neuroacoustic physics files that are fast acting, provide a deep recovery and restoration experience, and predictably balance the mind and body.

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According to Dr. Holloway, and many other leading scientists, all creation on this dimension is oscillatory. Mankind has become de-synchronized from the master oscillatory matrix. The greater the desynchronization, the greater the alienation and sense of isolation. We bring, with NuCalm, to the world, a technology that can re-synchronize and restore the lost complexity. NuCalm produces coherence in the heart, which is the true seat of intelligence. When the heart and brain connection is coherent, even dormant DNA potentials are released.

In the invention process Dr. Holloway focused on four critical areas of the brain:

  • Reticular activating system
  • Corpus callosum
  • HPA axis
  • Autonomic nervous system

To create effective neurobiofeedback within the complexities of the brain, Dr. Holloway leveraged the auditory motor cortex, not just as a gateway for collecting auditory signals, but for its function in stimulating the prefrontal and frontal motor cortex. The brain is nonlinear, thus using proprietary, complex methods to present patterns that the brain won’t easily get bored with is a significant challenge. The binaural signal processing, frequency-following-response neurobiofeedback is foundational to the software but cannot be the only effective elements. He also used specific techniques to evoke potential on a cellular level and increase electrical output focused on certain brain regions.

The NuCalm binaural signal processing entrains the brain to flow from everyday beta brain waves of consciousness to deeply healing and restorative theta brain waves. The neuroacoustic software acts like a Nascar pace car leading the mind to a profound state of restoration at the cellular level. The creative collaboration with music producer Dan Selene adds a further level of complexity to the tracks due to the synergy between the software driver portion and the carrier of the software, which is the music integration that augments the outcome for optimal performance. With NuCalm, one will experience deep restoration and balance, while predictably and safely managing stress on a personal level, without drugs or side effects.


STEP 1: NuCalm Supplementation – Topical Cream or Chewable Supplements

The first step is to apply a topical cream, or chew dietary supplements, that are designed to counteract adrenaline. The proprietary NuCalm formula provides the brain with the key nutrients and all-natural amino acids needed to relax.

STEP 2: Microcurrent Stimulation

Step two for NuCalm is to use a sub-sensory microcurrent to catalyze the effectiveness of the NuCalm supplementation. The combination of the supplementation and the microcurrent works on the midbrain to interrupt the body’s natural stress response. Research shows this microcurrent helps balance the brain’s neurochemistry by reestablishing optimal neurotransmitter levels. You won’t feel it while it’s working.

STEP 3: NuCalm Neuroacoustic Software App

We invented the world’s most sophisticated proprietary neuroacoustic software to oscillate brain wave function between deep relaxation and recovery. The physics used in the NuCalm software guides the brain to alpha and theta zones.

NuCalm Neuroacoustic Software Library in the NuCalm app lets you choose from a variety of soundtracks, including different types of music or nature sounds that all have the neuroacoustic beats built into them. The NuCalm app also lets you track your usage data so you can see how your usage is reflected in your daily performance.

STEP 4: Eye mask

Light-blocking eye masks help eliminate visual stimuli and maintain a deep state of relaxation.

The combination of these four components provides a fully immersive experience, erasing stress and anxiety to achieve a deep level of calm.